The All-in-One Breakthrough for Every Wound

Bonvadis® is a breakthrough topical cream clinically proven to accelerate healing across all wounds-including diabetic foot ulcers, venous and pressure ulcers, post-surgical wounds, and burns. Its unique and evidence-based formula delivers fast, safe, and effective results, even for the most challenging wounds.

Bonvadis® is indicated for prescription use (Rx)

The All-in-One Breakthrough for Every Wound

Bonvadis® is a breakthrough topical cream clinically proven to accelerate healing across all wounds-including diabetic foot ulcers, venous and pressure ulcers, post-surgical wounds, and burns. Its unique and evidence-based formula delivers fast, safe, and effective results, even for the most challenging wounds.

Bonvadis® is indicated for prescription use (Rx)

Feature and Benefits
Universal Applicability for All Wound Types

Bonvadis® is indicated for a wide spectrum of wounds— including acute wounds, chronic wounds such as DFU, post-surgical wounds, and 1stand 2nd degree burns. Its clinical versatility is supported by multinational clinical trials and regulatory approvals across the US, Saudi Arabia, and other key markets.

Universal Applicability for All Wound Types

Bonvadis® is indicated for a wide spectrum of wounds— including acute wounds, chronic wounds such as DFU, post-surgical wounds, and 1stand 2nd degree burns. Its clinical versatility is supported by multinational clinical trials and regulatory approvals across the US, Saudi Arabia, and other key markets.

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Clinically Proven Rapid Healing and Limb Salvage

Bonvadis® is backed by robust clinical evidence demonstrating significant improvements in complete healing rates and limb preservation. In both clinical and real-world studies, it delivers fast, effective results—even in high-risk patients.

Up to 80% complete healing observed in real-world studies, with many wounds closing within 2–6 weeks.

In a randomized controlled trial (RCT) for diabetic foot ulcers, Bonvadis® achieved a 60.7% healing rate, outperforming standard care (p=0.0001).

Significant reduction in amputation risk compared to the other advanced treatments.

Clinically Proven Rapid Healing and Limb Salvage
Before imageAfter image

Bonvadis® is backed by robust clinical evidence demonstrating significant improvements in complete healing rates and limb preservation. In both clinical and real-world studies, it delivers fast, effective results—even in high-risk patients.

Up to 80% complete healing observed in real-world studies, with many wounds closing within 2–6 weeks.

In a randomized controlled trial (RCT) for diabetic foot ulcers, Bonvadis® achieved a 60.7% healing rate, outperforming standard care (p=0.0001).

Significant reduction in amputation risk compared to the other advanced treatments.

Innovative Solution for All Stages

Bonvadis® supports healing across the full wound care continuum by creating an optimal moist microenvironment. It helps resolve chronic inflammation, promote epithelialization and support tissue remodeling with minimal scarring. It is especially effective for chronic, infected, or non-healing wounds, including those in high-risk patients such as individuals on dialysis.

Innovative Solution for All Stages

Bonvadis® supports healing across the full wound care continuum by creating an optimal moist microenvironment. It helps resolve chronic inflammation, promote epithelialization and support tissue remodeling with minimal scarring. It is especially effective for chronic, infected, or non-healing wounds, including those in high-risk patients such as individuals on dialysis.

Natural Botanical Formula, Safe for Long-Term Use

Bonvadis® gentle, botanical-based formulation is naturally free from immune rejection, infection risk, and proteolytic degradation. Clinically proven for long-term and repeated use, Bonvadis® helps minimize scarring with no reported adverse effects.

Natural Botanical Formula, Safe for Long-Term Use

Bonvadis® gentle, botanical-based formulation is naturally free from immune rejection, infection risk, and proteolytic degradation. Clinically proven for long-term and repeated use, Bonvadis® helps minimize scarring with no reported adverse effects.

Bonvadis®: Advanced Care Made Simple

Bonvadis® is designed as easy, effective wound care treatment. It requires no refrigeration and can be applied easily by a healthcare professional. It is a cost-efficient solution for long-term care as it accelerates healing time.

Bonvadis®: Advanced Care Made Simple

Bonvadis® is designed as easy, effective wound care treatment. It requires no refrigeration and can be applied easily by a healthcare professional. It is a cost-efficient solution for long-term care as it accelerates healing time.

Cost-Effective and Ready for Routine Clinical Use

Bonvadis® delivers superior cost-effectiveness compared to advanced therapies such as skin substitutes. It can be used as a standalone treatment or in combination with other modalities, including standard dressings, and negative pressure wound therapy (NPWT) , making it highly adaptable to diverse clinical settings and wound care protocols.

Cost-Effective and Ready for Routine Clinical Use

Bonvadis® delivers superior cost-effectiveness compared to advanced therapies such as skin substitutes. It can be used as a standalone treatment or in combination with other modalities, including standard dressings, and negative pressure wound therapy (NPWT) , making it highly adaptable to diverse clinical settings and wound care protocols.

Bonvadis® stands as the world’s most adaptable and clinically validated wound care solution-delivering rapid, safe, and cost-effective healing for all wound types – empowering patients and clinicians worldwide.
Expert Series
Plastic Surgeon Testimonial
Nurse Practitioner Testimonial
DPM Testimonial
Vascular Surgeon Testimonial
Podiatric Surgeon Testimonial

We’ve utilized the product basically and all the way through the algorithm. The product has just been superior to everything that we’ve been doing up to this point.

Dr. Brock A. LidenDPM, FABWH, FAPWCA
“We’ve utilized the product basically and all the way through the algorithm. The product has just been superior to everything that we’ve been doing up to this point.”

-Dr. Brock A. Liden/DPM, FABWH, FAPWCA

User Experience

Diabetic Foot Ulcer

A 100 cm2 Tendon-exposed DFU

  • Female aged 55 y/o
  • HbA1c: 13.2%,
  • Ulcer size: 100 cm2
  • Bonvadis® treatment results in good wound healing and avoided further amputation.

Diabetic Foot Ulcer

A Wagner grade 4 Ulcer Saved from Amputation

  • Female aged 77 y/o
  • Hypertensive and dialysis
  • Ulcer size : 60 cm2
  • Bonvadis management prevented the occurrence of further amputation.

Post-surgical Wound

  • Female aged 75 y/o
  • Nasal bone fracture
  • Wound length : 12 cm
  • Bonvadis® promoted scar maturation for 4 weeks.

2nd Degree Burn

  • Male aged 32 y/o
  • 2nd Degree Burn
  • Wound location : face, ears and neck
  • Healed in 1 week.
FAQ
Clinical Use

Can patients use Bonvadis® once per day?

Reapply as necessary or as directed until the wound or lesion has fully healed.

Can Bonvadis® be used with foam or other dressings?

Yes, after application of Bonvadis® to the affected area, appropriate dressing (e.g., foam, gauze, or other advanced wound dressings) can be used to cover the wound as directed by your healthcare provider.

May Bonvadis® be used alongside other wound care treatments (e.g negative pressure wound therapy (NPWT), oxygen therapy and compression therapy)?

Bonvadis® may be used alongside other wound care treatments, as directed by your healthcare professional, based on clinical assessment. (e.g negative pressure wound therapy (NPWT), oxygen therapy and compression therapy)

Application of Bonvadis® to the affected area(s) should continue during any subsequent physical therapy treatments.

Efficacy & Differentiation

Is Bonvadis® clinically proven? Are there clinical data?

Yes. In a head-to-head RCT (n=236), Bonvadis® outperformed standard care. It is ranked among the top 5 globally for DFU therapy, with robust efficacy including high-risk patients.

How fast is Bonvadis® in healing DFUs?

Bonvadis® shortens healing time by 100 days compared to best care (90.5 vs 141.5 days). In Egypt real-world study, average healing time was 5.2 weeks.

Is Bonvadis® more effective than other treatments?

Yes. Bonvadis® showed superior healing rates, faster recovery, and reduced amputation compared to current best care in both RCT and real-world settings.

Can Bonvadis® reduce the need for amputation?

Yes. A real-world study showed a reduction in amputation incidence from 22.7% (best care) to 3.5% with Bonvadis®.

What are the unique advantages of Bonvadis® compared to the available alternatives? Why should Bonvadis® be the preferred choice?

(1) The only wound bed optimization technology that demonstrates rapid granulation tissue growth in 7 days
(2) The etiology-driven technology for chronic wound healing via modulating wound environment
(3) Combination with systemic antibiotics in infected DFUs demonstrates superior effect
(4) Significant cost-saving evidence for treating DFUs
(5) Quality healing without hypertrophic scarring and improved mobility

Which institutes or regulatory authorities have officially adopted Bonvadis® in their Clinical Practice Guidelines?

Yes. Bonvadis® has been included in the following clinical practice guidelines and expert consensuses in Taiwan and China:
• DAROC Clinical Practice Guideline for Type 2 Diabetes Care 2022 (2024 update)
• 2024 TSOC/TSPS Joint Consensus: Strategies for Advanced Vascular Wound Management in Arterial and Venous Diseases
• Expert consensus on wound treatment of diabetic foot ulcer(2024) by Chinese Society of Endocrinology, China Endocrinology and Metabolism Specialist Alliance
• The book series “Chinese Series on Skin and Soft Tissue Injury Repair” – a key national book publishing project under the 14th Five-Year Plan and a recipient of the 2022 National Publishing Fund in China (ISBN: 978-7-5773-0444-1 for Elderly Skin and Soft Tissue Injury Repair and 978-7-5773-0445-8 for Cosmetic and Plastic Reconstruction)