About ONENESS

Our researchers are dedicated to addressing unmet medical needs, aiming to lead patients out of illness and drive transformative improvements in their lives. Oneness Biotech focuses on treating chronic skin and immune diseases, boasting a comprehensive and innovative portfolio. Notably, after 15 years of research, we have developed a first-in-class macrophage-regulator specifically designed to address chronic wounds affecting millions of patients.

The global diabetic population is estimated to exceed 640 million by 2030, with one in every three diabetes patients at risk of developing foot ulcers in their lifetime. Without early detection or comprehensive care, ulcers may lead to infections, gangrene, and even amputation. According to statistics, patients who undergo amputation face a staggering 70% risk of death within five years. As such, diabetic foot ulcers (DFU) are a severe and life-threatening complication.

Prior to the existence of “ON101”, there were no effective treatments that completely healed DFUs. “ON101” is an innovative product that rebalances the wound environment with novel mechanisms which regulate macrophages, thereby promoting necessary tissue repair for chronic wounds. The results of the international multicenter phase III clinical trial and its innovative drug mechanisms were published in JAMA Network Open in September 2021 and JID Innovations in June 2022 respectively.

Clinical trials show that compared to conventional wound dressings, “ON101” allowed twice as many patients to achieve complete wound healing. These results are statistically significant, advocating for the fact that the patients’ wounds were healed rapidly and thoroughly. This is a revolutionary breakthrough for the care of chronic wounds.

Oneness understands the prolonged agony experienced by patients without adequate medications for their unmet medical needs. Therefore, we dedicate extensive resources and time to the research and development of botanical drugs, small molecule drugs, and antibody drugs. Guided by our mission to nurture and care for life, we continuously strive to create new milestones in the scientific field. By enhancing collaboration with international pharmaceutical companies, we aspire to guide patients worldwide from the shadows of disease to the transformative dawn of healing, helping them reclaim their journey of life.