In DFU patients receiving NPWT, adding ON101 enhances granulation and epithelialization, supporting faster healing, shorter treatment duration, and lower risks of amputation and morbidity. As an adjunct to NPWT, ON101 may streamline wound recovery, lessen healthcare burden, and improve patient quality of life, highlighting its clinical and economic values in advanced wound care.
Diabetic foot ulcer (DFUs) often require negative pressure wound therapy (NPWT) to reduce wound size and prepare the wound bed for closure or grafting, yet many ulcers fail to achieve timely closure. This study evaluated whether combining ON101 topical cream with NPWT improves healing outcomes compared with standard of care (SOC) plus NPWT.